6.88 kcal/mol in cis- and 22.13 kcal/mol in transOH) and contributes
six.88 kcal/mol in cis- and 22.13 kcal/mol in transOH) and contributes most drastically toward the distinction in total interaction energy in CDK5. Residue Asn144, the analogue of Asp145 in CDK2,…